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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGAM1
All Species:
40
Human Site:
Y218
Identified Species:
97.78
UniProt:
P18669
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18669
NP_002620.1
254
28804
Y218
P
T
G
I
P
I
V
Y
E
L
D
K
N
L
K
Chimpanzee
Pan troglodytes
Q8MKE8
254
28790
Y218
P
T
G
I
P
I
V
Y
E
L
D
K
N
L
K
Rhesus Macaque
Macaca mulatta
XP_001087425
254
28784
Y218
P
T
G
I
P
I
V
Y
E
L
D
K
N
L
K
Dog
Lupus familis
XP_534980
254
28803
Y218
P
T
G
I
P
M
V
Y
E
L
D
K
N
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBJ1
254
28813
Y218
P
T
G
I
P
I
V
Y
E
L
D
K
N
L
K
Rat
Rattus norvegicus
P16290
253
28737
Y218
P
T
G
I
P
I
V
Y
E
L
N
Q
E
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516079
254
28495
Y218
P
T
G
I
P
I
V
Y
E
L
D
D
A
L
K
Chicken
Gallus gallus
Q5ZLN1
254
28880
Y218
P
T
G
I
P
I
V
Y
E
L
D
K
N
L
K
Frog
Xenopus laevis
NP_001086809
254
28776
Y218
P
T
G
I
P
I
V
Y
E
L
D
K
N
L
K
Zebra Danio
Brachydanio rerio
NP_001001408
254
28819
Y218
P
T
G
I
P
M
V
Y
E
L
D
K
N
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
99.6
99.6
N.A.
99.6
79.1
N.A.
79.1
92.9
86.2
98.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.4
100
100
N.A.
99.6
89.7
N.A.
88.9
97.2
92.9
99.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
80
N.A.
86.6
100
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
86.6
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
90
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
100
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
80
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
100
% K
% Leu:
0
0
0
0
0
0
0
0
0
100
0
0
0
100
0
% L
% Met:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
80
0
0
% N
% Pro:
100
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _